The ACR Antibody (C-term) from MyBioSource.com is a Rabbit Polyclonal antibody to ACR, and Acrosin. This antibody recognizes Human antigen. The ACR Antibody (C-term) has been validated for the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
ACR is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids